186895-51-2Relevant academic research and scientific papers
Total synthesis of stipiamide and designed polyenes as new agents for the reversal of multidrug resistance
Andrus, Merritt B.,Lepore, Salvatore D.,Turner, Timothy M.
, p. 12159 - 12169 (2007/10/03)
The synthesis of (-)-stipiamide (1) is reported together with the designed enynes 2 (6,7-dehydrostipiamide) and 3 that are now shown to reverse the multidrug resistance (MDR) of human breast cancer cells (MCF-7adrR). Stipiamide was assembled using a Still
