186895-77-2

Upstream product

• 862728-61-8 3-bromo-1-(tert-butyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
• 862728-60-7 1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 

Downstream Products

• 1354825-80-1 C₁₆H₂₀N₆ 
• 1354826-08-6 C₁₆H₁₈N₆O₂ 
• 1151650-87-1 1-pyrimidin-2-yl-3-p-tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine 

Relevant academic research and scientific papers

Microwave-assisted synthesis of N1- and C3-substituted pyrazolo[3,4-d] pyrimidine libraries

The parallel synthesis of a library N1- and C3-substituted-pyrazolo[3,4-d] pyrimidines is described. The microwave-assisted approach involves the de novo generation of the heterocyclic scaffold, facile alkylation at N1 via either a Mitsunobu or a direct alkylation reaction and arylation at C3 via a Suzuki reaction.