186982-44-5

Upstream product

• 172848-41-8 4-(3-trifluoromethylphenyl)-1,3-thiazol-2-amine 
• 349-76-8 3'-(trifluoromethyl)acetophenone 

Downstream Products

• 1391980-12-3 2-(2-amino-4-(3-(trifluoromethyl)phenyl)thiazol-5-yloxy)benzonitrile 
• 1391979-77-3 N-(5-(2-cyanophenoxy)-4-(3-(trifluoromethyl)phenyl)thiazol-2-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide 

Relevant academic research and scientific papers

NOVEL 2-ACYLAMINOTHIAZOLE DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF

The present invention relates to novel 2-acylaminothiazole derivatives. The present invention also relates to the preparation method for these novel 2-acylaminothiazole derivatives and intermediates thereof, and a pharmaceutical composition containing these compounds. Moreover, the present invention also relates to these novel 2-acylaminothiazole derivatives and the pharmaceutical composition containing the same for use in treatment and/or prevention of thrombopoietin receptor mediated diseases.

COMPOUNDS USEFUL AS RETINOID-RELATED ORPHAN RECEPTOR GAMMA MODULATORS

Disclosed are retinoid-related orphan receptor gamma (RORγ) modulators of Formula (I) and their use in the treatment of diseases mediated by RORγ, wherein the radicals have the meanings as defined in the invention.