187026-83-1

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 870-46-2 t-butoxycarbonylhydrazine 
• 637-59-2 1-Bromo-3-phenylpropane 

Downstream Products

• 259862-97-0 C₂₁H₂₁F₅N₂O₄ 
• 1026066-27-2 {1,1-dimethyl-2-oxo-2-[N'-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidine-1-carbonyl]-N'-(3-phenyl-propyl)-hydrazino]-ethyl}-carbamic acid tert-butyl ester 
• 1025872-50-7 N'-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidine-1-carbonyl]-N'-(3-phenyl-propyl)-hydrazinecarboxylic acid tert-butyl ester 
• 1026962-67-3 4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidine-1-carboxylic acid N-(3-phenyl-propyl)-hydrazide 

Relevant academic research and scientific papers

Iridium-catalyzed selective N-allylation of hydrazines

A highly chemo- and regioselective iridium-catalyzed allylic amination is described. The reaction of various hydrazones and hydrazides with allylic carbonates proceeds at ambient temperature in the presence of an [Ir(COD)Cl]2/pyridine catalyst,

Synthesis of azapeptides from hindered amines leading to novel growth hormone secretagogues

Preparations of aza analogues of known potent growth hormone secretagogues (GHS) were unsuccessful using known methods for preparation of azapeptides when hindered amines were employed. We now report a coupling method using bispentafluorophenylcarbonate as a 'balanced reactivity' phosgene equivalent to solve these problems.