18708-70-8

Basic information

• Product Name: 2,4,6-TRICHLORONITROBENZENE
• Synonyms: 1,3,5-trichloro-2-nitro-benzen;1-Nitro-2,4,6-trichlorobenzene;2,4,6-Trichloro-1-nitrobenzene;Benzene,1,3,5-trichloro-2-nitro-;1,3,5-TRICHLORO-2-NITROBENZENE;2,4,6-TRICHLORONITROBENZENE;2-Nitro-1,3,5-trichlorobenzene~2,4,6-Trichloronitrobenzene;2,4,6-TRICHLORONITROBENZENE OEKANAL,250
• CAS NO: 18708-70-8
• Molecular Formula: C₆H₂Cl₃NO₂
• Molecular Weight: 226.44
• EINECS: 242-518-1
• Product Categories: FINE Chemical & INTERMEDIATES;Nitro CompoundsVolatiles/ Semivolatiles;Alpha Sort;Analytical Standards;AromaticsChemical Class;Chemical Class;ChloroAnalytical Standards;Halogenated;TP - TZ;T-ZAlphabetic;Nitro Compounds;Nitrogen Compounds;Organic Building Blocks;Building Blocks;Chemical Synthesis;Nitro Compounds;Nitrogen Compounds;Organic Building Blocks
• Mol File: 18708-70-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 70-72 °C
• Boiling Point: 303.2 °C at 760 mmHg
• Flash Point: 137.2 °C
• Appearance: yellow solid
• Density: 1.651 g/cm³
• Vapor Pressure: 0.0017mmHg at 25°C
• Refractive Index: 1.609
• Storage Temp.: 2-8°C
• Solubility: methanol: 0.1 g/mL, clear
• Stability: Stable. Incompatible with strong bases, strong reducing agents, strong oxidizing agents.
• BRN: 2213282
• CAS DataBase Reference: 2,4,6-TRICHLORONITROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-TRICHLORONITROBENZENE(18708-70-8)
• EPA Substance Registry System: 2,4,6-TRICHLORONITROBENZENE(18708-70-8)

Safety Data

• Hazard Codes: T
• Statements: 23/24/25-33
• Safety Statements: 28-36/37/39-45
• RIDADR: UN 1578 6.1/PG 2
• WGK Germany: 3
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 18708-70-8(Hazardous Substances Data)

Usage

Chemical Properties

yellow solid

Uses

1,3,5-Trichloro-2-nitrobenzene is a building block for organic synthesis.

General Description

Needles in alcohol or light beige crystals.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2,4,6-TRICHLORONITROBENZENE is incompatible with strong bases and strong oxidizing agents.

Health Hazard

SYMPTOMS: Absorption of a similar chemical into the body leads to formation of methemoglobin which in sufficient concentration causes cyanosis.

Fire Hazard

Flash point data for 2,4,6-TRICHLORONITROBENZENE are not available; however, 2,4,6-TRICHLORONITROBENZENE is probably combustible.

InChI:InChI=1/C6H2Cl3NO2/c7-3-1-4(8)6(10(11)12)5(9)2-3/h1-2H

Upstream product

• 634-93-5 2,4,6-trichloroaniline 
• 74087-85-7 3,3-dimethyldioxirane 
• 108-70-3 1,3,5-trichlorobenzene 
• 7697-37-2 nitric acid 
• 99-09-2 3-nitro-aniline 
• 62406-71-7 2,4,6-trichloro-3-nitro-aniline 

Downstream Products

• 14227-18-0 1,3,5-trimethoxy-2-nitrobenzene 
• 74672-01-8 3,5-dichloro-2-nitroanisole 
• 83-21-6 5-chloro-1,3-dimethoxy-2-nitro-benzene 
• 857578-56-4 (3,5-dichloro-2-nitro-phenyl)-p-tolyl sulfide 
• 857578-95-1 5-chloro-2-nitro-1,3-bis-p-tolylsulfanyl-benzene 
• 860518-81-6 2-nitro-1,3,5-tris-p-tolylsulfanyl-benzene 
• 315-14-0 1,3,5-trifluoro-2-nitrobenzene 
• 1196-13-0 2,4,6-trichloronitrosobenzene 
• 84802-32-4 2,4,6-trichloronitrosobenzene dimer 
• 113864-61-2 2,6-diamino-4-chloro-nitrobenzene 
• 133387-43-6 C₁₄H₁₈ClN₃O₂ 
• 133387-45-8 C₁₈H₂₆N₄O₂ 
• 133387-40-3 4-(3,5-Dichloro-4-nitro-phenyl)-morpholine 
• 133387-37-8 2-morpholino-4,6-dichloro-1-nitrobenzene 

Relevant articles and documents

Ozone-mediated reaction of polychlorobenzenes and some related halogeno compounds with nitrogen dioxide: A novel non-acid methodology for the selective mononitration of moderately deactivated aromatic systems

In the presence of ozone and preferably methanesulfonic acid as catalyst, polychlorobenzenes undergo selective mononitration with nitrogen dioxide at low temperatures, giving the corresponding polychloronitrobenzenes, in most cases in nearly quantitative yields.

FUNCTIONAL GROUP OXIDATION USING SODIUM PERBORATE

Sodium perborate in acetic acid is an effective reagent for the oxidation of anilines to nitroarenes and of sulphides to either sulphoxides or sulphones.It is also an excellent reagent for the oxidative deprotection of ketone dimethylhydrazones.Baeyer-Villiger oxidation of ketones can be carried out with sodium perborate in either trifluoroacetic acid or acetic acid/trifluoroacetic acid mixtures, and hydroquinones and certain highly substituted phenols are smoothly converted into quinones.