187085-39-8

Basic information

• Product Name: 2-[[2-(4-Nitro-phenyl)-ethyl]-(5-oxo-7-trimethylsilanyl-hept-6-ynoyl)-amino]-propionic acid
• Synonyms: 2-[[2-(4-Nitro-phenyl)-ethyl]-(5-oxo-7-trimethylsilanyl-hept-6-ynoyl)-amino]-propionic acid
• CAS NO: 187085-39-8
• Molecular Weight: 432.549
• Mol File: 187085-39-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-[[2-(4-Nitro-phenyl)-ethyl]-(5-oxo-7-trimethylsilanyl-hept-6-ynoyl)-amino]-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[[2-(4-Nitro-phenyl)-ethyl]-(5-oxo-7-trimethylsilanyl-hept-6-ynoyl)-amino]-propionic acid(187085-39-8)
• EPA Substance Registry System: 2-[[2-(4-Nitro-phenyl)-ethyl]-(5-oxo-7-trimethylsilanyl-hept-6-ynoyl)-amino]-propionic acid(187085-39-8)

Safety Data

• Hazardous Substances Data: 187085-39-8(Hazardous Substances Data)

Upstream product

• 187085-65-0 2-[[2-(4-Nitro-phenyl)-ethyl]-(5-oxo-7-trimethylsilanyl-hept-6-ynoyl)-amino]-propionic acid methyl ester 
• 14630-40-1 Bis(trimethylsilyl)ethyne 
• 187085-91-2 N-(4-nitrophenethyl)alanine methyl ester 
• 187085-44-5 7-(trimethylsilyl)-5-oxohept-6-ynoic acid 
• 29968-78-3 2-(4-nitrophenyl)ethylamine monohydrochloride 
• 24954-67-4 2-(p-nitrophenyl)ethylamine 
• 108-55-4 glutaric anhydride, 

Relevant articles and documents

A simple and general synthesis of 4-oxo-4,5,6,7-tetrahydroindoles via a novel intramolecular 1,3-dipolar cycloaddition approach

A general synthesis of 4-keto-4,5,6,7-tetrahydroindoles 6-12 has been achieved in two steps using a new intramolecular 1,3-dipolar cycloaddition approach in moderate yields (45-60%). The potential of this methodology is demonstrated by the synthesis of a mitomycin skeleton (15) and a topoisomerase-1 inhibitor skeleton (17).