187086-86-8

Basic information

• Product Name: 2-(3,5-dichloro-phenyl)-1,3-dimethyl-2,3-dihydro-1H-benzoimidazole
• CAS NO: 187086-86-8
• Molecular Weight: 293.196
• Mol File: 187086-86-8.mol

Chemical Properties

• CAS DataBase Reference: 2-(3,5-dichloro-phenyl)-1,3-dimethyl-2,3-dihydro-1H-benzoimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,5-dichloro-phenyl)-1,3-dimethyl-2,3-dihydro-1H-benzoimidazole(187086-86-8)
• EPA Substance Registry System: 2-(3,5-dichloro-phenyl)-1,3-dimethyl-2,3-dihydro-1H-benzoimidazole(187086-86-8)

Safety Data

• Hazardous Substances Data: 187086-86-8(Hazardous Substances Data)

Upstream product

• 74-88-4 methyl iodide 

Relevant articles and documents

Reactivities of acridine compounds in hydride transfer reactions

Reactivities of acridine derivatives (10-benzylacridinium ion, 1a +, 10-methylacridinium ion, 1b+, and 10-methyl-9- phenylacridinium ion, 1c+) have been compared quantitatively for hydride transfer reactions with 1,3-dimethyl-2-substituted phenylbenzimidazoline compounds, 2Ha-h. Reactions were monitored spectrophotometrically in a solvent consisting of four parts of 2-propanol to one part of water by volume at 25 ± 0.1°C. Reduction potentials have been estimated for acridine derivatives by assuming that the equilibrium constants for the reductions of 1a+-c+ by 2Hb would be the same in aqueous solution and accepting -361 mV as the reduction potential of the 1-benzyl-3- carbamoylpyridinium ion. The resulting reduction potentials, E redo, are -47 mV for 1a+, -79 mV for 1b +, and -86 mV for 1c+. Each of acridine derivatives gives a linear Bronsted plot for hydride transfer reactions. The experimental slopes were compared with those obtained by Marcus theory. This comparison shows that the kinetic data are consistent with a one-step mechanism involving no high-energy intermediates. Copyright

Marcus theory of a parallel effect on α for hydride transfer reaction between NAD+ analogues

Rate and equilibrium constants for hydride transfer from a series of 1,3-dimethyl-2-substituted phenylbenzimidazolines to a pyridinium ion, a quinolinium ion, and a phenanthridinium ion have been evaluated. Each oxidizing agent gives a linear Bronsted plot with slope, α. The α values vary systematically with the spontaniety of the reactions. They are in reasonable agreement with the predictions of modified Marcus theory. Their trend is very accurately predicted, showing a parallel (Leffler-Hammond) effect. These results make a multistep mechanism, involving high energy intermediates, very unlikely.