(TYR0)-UROCORTIN (RAT) is a synthetic analog of urocortin, a peptide hormone found in the brain and other tissues. It functions as a ligand for the corticotropin-releasing factor receptor 2 (CRF2) and has demonstrated significant anxiolytic and cardiovascular effects in animal models. (TYR0)-UROCORTIN (RAT) has been investigated for its potential therapeutic applications in treating anxiety disorders and cardiovascular diseases, as well as serving as a research tool to enhance understanding of the physiological effects of the urocortin peptide family and the CRF2 receptor.
187111-93-9
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Basic information
- Product Name: (TYR0)-UROCORTIN (RAT)
- Synonyms: H-TYR-ASP-ASP-PRO-PRO-LEU-SER-ILE-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-THR-LEU-LEU-GLU-LEU-ALA-ARG-THR-GLN-SER-GLN-ARG-GLU-ARG-ALA-GLU-GLN-ASN-ARG-ILE-ILE-PHE-ASP-SER-VAL-NH2;(TYR0)-UROCORTIN (RAT)
- CAS NO:187111-93-9
- Molecular Formula: C215H347 N63 O66
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: Other Peptides;Peptides and Proteins;Peptides for Cell Biology
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /lyophilized powder (hygroscopic)
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: (TYR0)-UROCORTIN (RAT)(CAS DataBase Reference)
- NIST Chemistry Reference: (TYR0)-UROCORTIN (RAT)(187111-93-9)
- EPA Substance Registry System: (TYR0)-UROCORTIN (RAT)(187111-93-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 187111-93-9(Hazardous Substances Data)
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187111-93-9 Usage
Uses
Used in Pharmaceutical Applications:(TYR0)-UROCORTIN (RAT) is used as a therapeutic agent for the treatment of anxiety disorders due to its potent anxiolytic effects observed in various animal models. It modulates the activity of the CRF2 receptor, which is implicated in the regulation of stress and anxiety responses.
Used in Cardiovascular Applications:
(TYR0)-UROCORTIN (RAT) is used as a therapeutic agent for the treatment of cardiovascular diseases. Its cardiovascular effects, including potential benefits in heart failure and other related conditions, make it a promising candidate for further research and development in this field.
Used in Research and Development:
(TYR0)-UROCORTIN (RAT) is used as a research tool to better understand the physiological effects of the urocortin peptide family and the CRF2 receptor. This knowledge can contribute to the development of new therapeutic strategies for anxiety disorders and cardiovascular diseases.
Used in Drug Delivery Systems:
While not explicitly mentioned in the provided materials, it can be inferred that (TYR0)-UROCORTIN (RAT) may also be used in the development of novel drug delivery systems to improve its bioavailability, delivery, and therapeutic outcomes in the treatment of anxiety disorders and cardiovascular diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 187111-93-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,1,1 and 1 respectively; the second part has 2 digits, 9 and 3 respectively.Calculate Digit Verification of CAS Registry Number 187111-93:
(8*1)+(7*8)+(6*7)+(5*1)+(4*1)+(3*1)+(2*9)+(1*3)=139
139 % 10 = 9
So 187111-93-9 is a valid CAS Registry Number.
187111-93-9Upstream product
187111-93-9Downstream Products
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(TYR0)-UROCORTIN (RAT)
