187164-04-1 Usage
General Description
The chemical (3-Benzyloxycarbonylamino-2-oxo-6-propyl-2H-pyridin-1-yl)-acetic acid tert-butyl ester is a compound with the molecular formula C24H28N2O5. It is a tert-butyl ester derivative of a pyridine derivative with a benzyloxycarbonylamino group and an acetic acid moiety. (3-Benzyloxycarbonylamino-2-oxo-6-propyl-2H-pyridin-1-yl)-acetic acid tert-butyl ester may have potential applications in medicinal chemistry, particularly in the development of new pharmaceuticals and drug candidates. Further research is needed to fully understand its properties and potential uses in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 187164-04-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,1,6 and 4 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 187164-04:
(8*1)+(7*8)+(6*7)+(5*1)+(4*6)+(3*4)+(2*0)+(1*4)=151
151 % 10 = 1
So 187164-04-1 is a valid CAS Registry Number.
187164-04-1Relevant articles and documents
C6 modification of the pyridinone core of thrombin inhibitor L-374,087 as a means of enhancing its oral absorption
Isaacs, Richard C. A.,Cutrona, Kellie J.,Newton, Christina L.,Sanderson, Philip E. J.,Solinsky, Mark G.,Baskin, Elizabeth P.,Chen, I-Wu,Cooper, Carolyn M.,Cook, Jacquelynn J.,Gardell, Stephen J.,Lewis, S. Dale,Lucas Jr., Robert J.,Lyle, Elizabeth A.,Lynch Jr., Joseph J.,Naylor-Olsen, Adel M.,Stranieri, Maria T.,Vastag, Kari,Vacca, Joseph P.
, p. 1719 - 1724 (2007/10/03)
1 (L-374,087) is a potent, selective, efficacious, and orally bioavailable thrombin inhibitor that contains a core 3-amino-2-pyridinone moiety. Replacement of the C6 pyridinone metyl group of 1 by a propyl group gave 5 (L-375,052), which retained all the excellent properties of 1, and also yielded higher plasma levels after oral dosing in dogs and rats.
