187235-47-8 Usage
General Description
The chemical compound "(6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4-(trifluoromethoxy)phenyl]carbamate" is a complex organic molecule that consists of a nitro group, a dihydro-imidazo ring, an oxazin ring, and a carbamate functional group attached to a phenyl ring with a trifluoromethoxy substituent. (6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4-(trifluoromethoxy)phenyl]carbamate has a stereocenter at the 6th position, and the stereochemistry is specified as (6S). It is likely to have pharmacological or biological properties or is used as a research tool in medicinal chemistry due to its complex structure and the presence of a carbamate group, which is often found in pharmaceuticals and bioactive compounds. Additionally, its nitro group may contribute to its reactivity or pharmacological activity.
Check Digit Verification of cas no
The CAS Registry Mumber 187235-47-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,2,3 and 5 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 187235-47:
(8*1)+(7*8)+(6*7)+(5*2)+(4*3)+(3*5)+(2*4)+(1*7)=158
158 % 10 = 8
So 187235-47-8 is a valid CAS Registry Number.
187235-47-8Relevant articles and documents
Structure-activity relationships for amide-, carbamate-, and urea-linked analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl] oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)
Blaser, Adrian,Palmer, Brian D.,Sutherland, Hamish S.,Kmentova, Iveta,Franzblau, Scott G.,Wan, Baojie,Wang, Yuehong,Ma, Zhenkun,Thompson, Andrew M.,Denny, William A.
experimental part, p. 312 - 326 (2012/03/07)
Analogues of clinical tuberculosis drug (6S)-2-nitro-6-{[4- (trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824), in which the OCH2 linkage was replaced with amide, carbamate, and urea functionality, were investigate
