187235-48-9 Usage
Chemical structure
The compound consists of a urea group attached to a nitro-substituted imidazole ring and a trifluoromethoxyphenyl group.
Stereochemistry
The compound has a 6S stereochemistry at the imidazole ring.
Functional groups
The compound contains a nitro group (-NO2), a urea group (-NH-CO-NH-), and a trifluoromethoxy group (-OCF3).
Potential applications
It is a potential drug candidate with various pharmaceutical applications, including as an antiviral or antineoplastic agent.
Mechanism of action
The compound may have therapeutic effects through its ability to inhibit specific enzymes or receptors in biological systems.
Ongoing research
Further research is ongoing to determine the exact mechanisms of action and potential benefits of this chemical compound for medical and scientific use.
Check Digit Verification of cas no
The CAS Registry Mumber 187235-48-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,2,3 and 5 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 187235-48:
(8*1)+(7*8)+(6*7)+(5*2)+(4*3)+(3*5)+(2*4)+(1*8)=159
159 % 10 = 9
So 187235-48-9 is a valid CAS Registry Number.
187235-48-9Relevant articles and documents
Structure-activity relationships for amide-, carbamate-, and urea-linked analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl] oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)
Blaser, Adrian,Palmer, Brian D.,Sutherland, Hamish S.,Kmentova, Iveta,Franzblau, Scott G.,Wan, Baojie,Wang, Yuehong,Ma, Zhenkun,Thompson, Andrew M.,Denny, William A.
experimental part, p. 312 - 326 (2012/03/07)
Analogues of clinical tuberculosis drug (6S)-2-nitro-6-{[4- (trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824), in which the OCH2 linkage was replaced with amide, carbamate, and urea functionality, were investigate
