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187344-68-9

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187344-68-9 Usage

General Description

(6-Bromo-8-(methylamino)imidazo[1,2-a]pyrazin-3-yl)methanol is a chemical compound with a molecular formula C9H10BrN5O. It is a white to off-white solid that is mainly used as a reagent or intermediate in the synthesis of various pharmaceutical compounds. It is also used in the research and development of new drugs due to its potential pharmacological properties. The compound contains a bromine atom, a methylamino group, and a hydroxyl group, and it belongs to the class of imidazo[1,2-a]pyrazine derivatives. Due to its structural features, it may exhibit biological activity and is of interest in medicinal chemistry research.

Check Digit Verification of cas no

The CAS Registry Mumber 187344-68-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,3,4 and 4 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 187344-68:
(8*1)+(7*8)+(6*7)+(5*3)+(4*4)+(3*4)+(2*6)+(1*8)=169
169 % 10 = 9
So 187344-68-9 is a valid CAS Registry Number.

187344-68-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name [6-bromo-8-(methylamino)imidazo[1,2-a]pyrazin-3-yl]methanol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:187344-68-9 SDS

187344-68-9Downstream Products

187344-68-9Relevant articles and documents

Synthesis and Antibronchospastic Activity of 8-Alkoxy- and 8-(Alkylamino)imidazopyrazines

Bonnet, Pierre A.,Michel, Alain,Laurent, Florence,Sablayrolles, Claire,Rechencq, Eliane,et al.

, p. 3353 - 3358 (2007/10/02)

Theophylline still occupies a dominant place in asthma therapy.Unfortunatly its adverse central nervous system (CNS) stimulant effects can dramatically limit its use, and adjustments in the dosage are often needed.We have synthesized a new series of imidazopyrazine derivatives which are much more potent bronchodilators than theophylline in vivo and do not exhibit the CNS stimulatory profile.In vitro studies on isolated rat uterus and guinea pig trachea confirm the high potentialities of these derivatives. 6-Bromo-8-(methylamino)imidazopyrazine-3-carbonitrile (23) is identified as the most potent compound of the series.As i n the case of theophylline, phosphodiesterase inhibition appears unlikely to be the unique mechanism of the action of this series of heterocycles.

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