18736-53-3

Basic information

• Product Name: bromodeoxyuridine triphosphate
• Synonyms: bromodeoxyuridine triphosphate
• CAS NO: 18736-53-3
• Molecular Formula: C9H14 Br N2 O14 P3
• Molecular Weight: 547.04
• Mol File: 18736-53-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 2.23g/cm³
• Refractive Index: 1.649
• CAS DataBase Reference: bromodeoxyuridine triphosphate(CAS DataBase Reference)
• NIST Chemistry Reference: bromodeoxyuridine triphosphate(18736-53-3)
• EPA Substance Registry System: bromodeoxyuridine triphosphate(18736-53-3)

Safety Data

• Hazardous Substances Data: 18736-53-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H14BrN2O14P3/c10-4-2-12(9(15)11-8(4)14)7-1-5(13)6(24-7)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h2,5-7,13H,1,3H2,(H,19,20)(H,21,22)(H,11,14,15)(H2,16,17,18)/t5-,6+,7+/m0/s1

Relevant articles and documents

SYNTHESIS OF TRITIUM-LABELED NUCLEOSIDE 5'-TRIPHOSPHATES AND NUCLEOSIDE 5'-DIPHOSPHATES

Tritium-labeled nucleoside 5'-triphosphates (NTPs) nucleoside 5'-diphosphates (NDPs) containing the tritium label in position 8 (in the purine nucleus) and 5 (in the pyrimidine nucleus) have been obtained by the dehalogenation of the corresponding bromine derivatives with gasous tritium.The dehalogenation of the Br-NTPs and Br-NDPs was carried out at atmospheric pressure in an aqueous alkaline medium using palladium catalysts (5percent Pd/BaSO4 or α-Pd).The possibility of introducing a tritium label into nucleotides of adenine series by the heterogeneous isotope exchange reaction with gaseous tritium in the presence of 5percent Pd/BaSO4 has been investigated.For the compounds synthesized, the compositions of the eluents used for the chromatographic isolation of the desired products are given.The molar activities of the compounds synthesized were between 370 and 740 TBq/mole (10-20 kCi/mole).