18740-26-6 Usage
General Description
(Thieno[2,3-d]pyrimidin-4-ylthio)acetic acid, also known as TPAA, is a chemical compound with potential pharmaceutical applications. It is a thienopyrimidine derivative with a thiol group and a carboxylic acid group. (THIENO[2,3-D]PYRIMIDIN-4-YLTHIO)ACETIC ACID is of interest in the development of new drugs for the treatment of various diseases, including cancer, inflammation, and neurological disorders. TPAA may act as an inhibitor of certain enzymes or receptors in the body, making it a potential candidate for the targeted treatment of specific conditions. Research on the biological and pharmacological properties of (Thieno[2,3-d]pyrimidin-4-ylthio)acetic acid is ongoing to determine its full potential in the field of medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 18740-26-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,7,4 and 0 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 18740-26:
(7*1)+(6*8)+(5*7)+(4*4)+(3*0)+(2*2)+(1*6)=116
116 % 10 = 6
So 18740-26-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H6N2O2S2/c11-6(12)3-14-8-5-1-2-13-7(5)9-4-10-8/h1-2,4H,3H2,(H,11,12)
18740-26-6Relevant articles and documents
QUINOLINONE DERIVATIVES AS METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS
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Paragraph 0245, (2021/12/31)
Disclosed herein are certain quinolinone derivatives of Formula (A) that are methionine adenosyltransferase 2A (MAT2A) inhibitors. Also disclosed are pharmaceutical compositions comprising such compounds and methods of treating diseases treatable by inhibition of MAT2A such as cancer, including cancers characterized by reduced or absence of methylthioadenosine phosphorylase (MTAP) activity.
