187400-18-6Relevant articles and documents
Syntheses and structure-activity relationships of 5,6,7,8-tetrahydro- 5,5,8,8-tetramethyl-2-quinoxaline derivatives with retinoic acid receptor α agonistic activity
Kikuchi, Kouichi,Hibi, Shigeki,Yoshimura, Hiroyuki,Tokuhara, Naoki,Tai, Kenji,Hida, Takayuki,Yamauchi, Toshihiko,Nagai, Mitsuo
, p. 409 - 419 (2000)
In the course of our studies on retinoic acid receptor (RAR) agonists, we have designed and synthesized a series of quinoxaline derivatives. One of them, 4-[5-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-quinoxalinyl)-1H-2- pyrrolyl]benzoic acid (3a), which