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4-[4-(1-tert-butyl-5-isopropyl-1H-pyrazol-3-yl)-4-oxo-butyryl]-benzoic acid methyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

187402-72-8

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187402-72-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 187402-72-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,4,0 and 2 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 187402-72:
(8*1)+(7*8)+(6*7)+(5*4)+(4*0)+(3*2)+(2*7)+(1*2)=148
148 % 10 = 8
So 187402-72-8 is a valid CAS Registry Number.

187402-72-8Downstream Products

187402-72-8Relevant academic research and scientific papers

Novel retinoic acid receptor α agonists: Syntheses and evaluation of pyrazole derivatives

Kikuchi, Kouichi,Hibi, Shigeki,Yoshimura, Hiroyuki,Tai, Kenji,Hida, Takayuki,Tokuhara, Naoki,Yamauchi, Toshihiko,Nagai, Mitsuo

, p. 619 - 622 (2007/10/03)

We have designed and synthesized a series of pyrazole derivatives as candidate retinoic acid receptor (RAR) agonists. One of them, 4-[5-(1, 5-diisopropyl-1H-3-pyrazolyl)-1H-2-pyrrolyl]benzoic acid (11b), which possesses a 2,5-disubstituted pyrrole moiety, showed selective transactivation activity for the RARα receptor, and had highly potent cell-differentiating activity on HL-60 cells. (C) 2000 Elsevier Science Ltd. All rights reserved.

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