187410-92-0

Upstream product

• 187410-90-8 1-(benzoyloxy)-5-methylideneheptan-6-one 
• 187410-91-9 2-[1-(4-cyclopenta-2,4-dienylidenebutyl)vinyl]-2-methyl-1,3-dioxolane 
• 187410-89-5 5-(2-methyl-1,3-dioxolan-2-yl)hex-5-enal 
• 187411-03-6 5-(2-methyl-1,3-dioxolan-2-yl)hex-5-en-1-ol 
• 123-54-6 acetylacetone 
• 542-92-7 cyclopenta-1,3-diene 

Relevant academic research and scientific papers

Diyl trapping reactions to synthesize taxol analogs

A new and efficient entry to the ABC-ring system common to taxol and related materials has been developed. Highlights include the use of a regioselective intramolecular diyl trapping reaction to synthesize tricyclic alkene 5, the creation and oxidative cleavage of the tetrasubstituted olefin found in ketal 20a,b to afford a highly functionalized eight-membered ring (21a), and cyclization of 22, thereby providing the tricyclic core.