18753-11-2Relevant academic research and scientific papers
Concave reagents. 20. Sterically shielded m-terphenyls as selective agents in general protonations
Luening,Baumgartner,Manthey,Meynhardt
, p. 7922 - 7926 (1996)
New m-terphenyls with acidic substituants in the 2′-position have been used in general protonations leading to reagent-controlled selectivity enhancements: up to 96:4 for the γ/α-protonation of unsymmetrically substituted allyl anions, up to 97:3 for the protonation of cyclohexyl anions generating preferentially the thermodynamically less stable cis-products. In order to allow a general, reagent-controlled protonation the acidity of the protonating agent should be as low as possible.
