187665-65-2

Basic information

• Product Name: (1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE
• Synonyms: (1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE;PNU 142633
• CAS NO: 187665-65-2
• Molecular Formula: C24H30N4O3
• Molecular Weight: 422.52
• Mol File: 187665-65-2.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Store at +4°C
• CAS DataBase Reference: (1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE(187665-65-2)
• EPA Substance Registry System: (1S)-1-[2-[4-[4-(AMINOCARBONYL)PHENYL]-1-PIPERAZINYL]ETHYL]-3,4-DIHYDRO-N-METHYL-1H-2-BENZOPYRAN-6-CARBOXAMIDE(187665-65-2)

Safety Data

• Hazardous Substances Data: 187665-65-2(Hazardous Substances Data)

Usage

Uses

PNU 142633 is a high affinity SR-1D agonist.

Biological Activity

Very selective, high affinity 5-HT 1D receptor agonist (K i values are 6 and > 18000 nM at human 5-HT 1D and 5-HT 1B receptors respectively). Inhibits sympathetically-induced tachycardic responses and blocks neurogenic plasma protein extravasation in vivo .