187670-17-3Relevant academic research and scientific papers
Chromogenic and fluorogenic "off-on-off" chemosensor for selective and sensitive detection of aluminum (Al3+) and bifluoride (HF2-) ions in solution and in living Hep G2 cells: Synthesis, experimental and theoretical studies
Manna, Saikat Kumar,Mondal, Debasish,Mukhopadhyay, Subrata,Pal, Kunal,Pathak, Sudipta,Pramanik, Samit
, p. 13259 - 13265 (2020)
A simple pyridine-dicarbohydrazide based colorimetric and fluorometric chemosensor L was designed and synthesized for Al3+ ion sensing in organo aqueous solution. In the presence of Al3+ ions, probe L exhibited visible color changes and fluorescence enhancement (20-fold) due to Al3+ induced chelation-enhanced fluorescence (CHEF) effects. Chemosensor L revealed high selectivity toward Al3+ ions by "turn-on"fluorescence among the other competitive metal ions examined with a detection limit of 0.8 μM. Probe L was found to bind with Al3+ ions in a 1 : 2 (probe : metal) stoichiometric fashion, with an association constant (Ka) of 4.26 × 104 M-2. In addition, DFT and TDDFT calculations were carried out to recognize the binding nature and electronic properties of probe L and its Al-complex. Furthermore, the in situ prepared [L-Al] complex was able to detect HF2- anions via a metal displacement strategy. The bioimaging application of Al3+ and HF2- was implemented in living human liver cancer cells (Hep G2). This journal is
