187680-75-7

Basic information

• Product Name: 4,5-Dihydropyrido[1,2-a][1,3]thiazolo[5,4-g]benzimidazol-2-amine
• Synonyms: YJA-20379-5
• CAS NO: 187680-75-7
• Molecular Formula: C₁₂H₁₀N₄S
• Molecular Weight: 242.3043
• Mol File: 187680-75-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,5-Dihydropyrido[1,2-a][1,3]thiazolo[5,4-g]benzimidazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-Dihydropyrido[1,2-a][1,3]thiazolo[5,4-g]benzimidazol-2-amine(187680-75-7)
• EPA Substance Registry System: 4,5-Dihydropyrido[1,2-a][1,3]thiazolo[5,4-g]benzimidazol-2-amine(187680-75-7)

Safety Data

• Hazardous Substances Data: 187680-75-7(Hazardous Substances Data)

Relevant articles and documents

Heterocycle-fused thiazole derivatives

PCT No. PCT/KR96/00082 Sec. 371 Date Jul. 3, 1997 Sec. 102(e) Date Jul. 3, 1997 PCT Filed Jun. 1, 1996 PCT Pub. No. WO97/03076 PCT Pub. Date Jan. 30, 1997A thiazole compound represented by general formula (I), wherein R is hydrogen atom, a hydroxy group, a straight or branched C1-C6 lower alkyl group, a C1-C4 lower alkoxy group, phenyl group, a phenyl group having one to three substituents selected from a group consisting of a C1-C4 lower alkyl group, a C1-C4 lower alkoxy group, fluorine, chlorine, bromine and an amino group, a C1-C5 alkylphenyl group, a phenyl group having one to three substituents selected from a group consisting of a C1-C4 lower alkyl group, a C1-C4 lower alkoxy group, fluorine, chlorine, bromine and an amino group, a substituted or unsubstituted guanidino group, or an amino group having a general formula: NR3R4 in which R3 and R4, identical to or different from each other, represent independently a hydrogen atom, a C1-C6 lower alkyl group, a C3-C6 cycloalkyl group, a substituted or unsubstituted pyridyl group, a phenyl group having one to three substituents selected from a group consisting of a C1-C4 lower alkyl group, a C1-C4 lower alkoxy group, a halogen atom, an amino group, a cyano group and a nitro group, a piperidine group or C1-C4 alkylpiperidine group; R1 and R2, identical to or different from each other, are independently a hydrogen atom, a hydroxy group, a C1-C6 lower alkyl group, phenyl group, a phenyl group having one substituent selected from a group consisting of a C1-C4 lower alkyl group, a C1-C4 lower alkoxy group, a halogen atom, a nitro and a cyano group, a C1-C5 alkylphenyl group, or a pyridine group; R5, R6, R7 and R8, identical to or different from each other, are independently a hydrogen atom, a hydroxy group, a C1-C4 lower alkyl group, a C1-C4 lower alkoxy group, phenyl group, or a phenyl group substituted with a C1-C4 alkyl group, a C1-C4 alkoxy group or a halogen atom, or a C1-C3 alkylphenyl group; Het is a 3-, 4- or 5-membered unsaturated monocyclic group, or 6- to 12-membered unsaturated fused cyclic group, said monocyclic and fused cyclic group being comprised of one or more hetero atoms selected from oxygen, oxidative nitrogen and oxidative sulfur atom are disclosed. These compounds show excellent anti-ulcer activity.