187729-29-9

Basic information

• Product Name: 9-[(2S,3R,4S,5R,6R)-3,5-Dihydroxy-6-hydroxymethyl-4-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yloxy]-nonanoic acid methyl ester
• CAS NO: 187729-29-9
• Molecular Weight: 512.552
• Mol File: 187729-29-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 9-[(2S,3R,4S,5R,6R)-3,5-Dihydroxy-6-hydroxymethyl-4-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yloxy]-nonanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 9-[(2S,3R,4S,5R,6R)-3,5-Dihydroxy-6-hydroxymethyl-4-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yloxy]-nonanoic acid methyl ester(187729-29-9)
• EPA Substance Registry System: 9-[(2S,3R,4S,5R,6R)-3,5-Dihydroxy-6-hydroxymethyl-4-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yloxy]-nonanoic acid methyl ester(187729-29-9)

Safety Data

• Hazardous Substances Data: 187729-29-9(Hazardous Substances Data)

Upstream product

• 161453-82-3 8-Methoxycarbonyloctyl 2-O-benzyl-4,6-O-p-methoxy-benzylidene-3-O-(3,4,6-tri-O-benzyl-α-D-glucopyranosyl)-α-D-glucopyranoside 

Relevant articles and documents

Synthesis of α-D-Glcp-(1→2)-α-D-Glcp-(1→3)-α-D-Glcp-O-(CH2)8COOh3 for use in the assay of α-glucosidase I activity

The chemical synthesis of α-D-Glcp-(1 → 2)-α-D-Glc p-(1 → 3)-α-D-Glcp-O-(CH2)8COOCH3 (9), a substrate specific for α-glucosidase I, is reported. This enzyme removes the terminal α-D-Glcp unit to produce α-D-Glcp-α-D-Glcp-(1 → 3) -α-D-Glcp-O-(CH2)8COOCH3 (10). This is the first synthetic substrate described for glucosidase I that allows kinetic evaluation of substrates and inhibitors of this enzyme. Tetramethylrhodamine was coupled to 9 through an ethylenediamine linker to produce a brilliant red derivative. Addition of this fluorescent dye did not affect enzyme binding to the substrate, as determined by a comparison of the K(m) value (1.3 mM). The fluorescent label allows visual detection of 2-3 pmol of product by TLC.