187752-85-8Relevant academic research and scientific papers
AMINO ACID DERIVATIVES
-
Page column 35, (2010/01/30)
There is provided amino acid derivatives of formula I, wherein p, q, R 1, R 2, R 3, R 4, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
Thrombin inhibitors, their preparation and use
-
, (2008/06/13)
PCT No. PCT/SE96/00878 Sec. 371 Date Aug. 7, 1996 Sec. 102(e) Date Aug. 7, 1996 PCT Filed Jul. 2, 1996 PCT Pub. No. WO97/02284 PCT Pub. Date Jan. 23, 1997There is provided amino acid derivative formula I, wherein p, q, R1, R2, R3, R4, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
