1878-58-6

Usage

Uses

Used in Research and Chemical Synthesis:
((2,3-dihydro-1H-inden-5-yl)oxy)acetic acid is utilized as a chemical intermediate for the synthesis of various complex organic molecules. Its reactivity and structural features make it a valuable building block in the development of new compounds and materials.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, ((2,3-dihydro-1H-inden-5-yl)oxy)acetic acid is employed as a potential active ingredient or a key component in the formulation of drugs. Its properties may contribute to the development of novel therapeutic agents, particularly in the areas of medicinal chemistry and drug discovery.
Used in Agrochemical Industry:
((2,3-dihydro-1H-inden-5-yl)oxy)acetic acid is used as a starting material or a component in the production of agrochemicals, such as pesticides and herbicides. Its chemical properties may offer new ways to control pests and weeds in agriculture, potentially leading to more effective and environmentally friendly products.

InChI:InChI=1/C11H12O3/c12-11(13)7-14-10-5-4-8-2-1-3-9(8)6-10/h4-6H,1-3,7H2,(H,12,13)/p-1

Upstream product

• 1470-94-6 5-hydroxy-2,3-dihydro-1H-indene 
• 860540-38-1 inden-5-yloxy-acetic acid 
• 79-08-3 bromoacetic acid 
• 64-17-5 ethanol 
• 860540-36-9 inden-5-yloxy-acetic acid ethyl ester 
• 97024-08-3 ethyl 2-(2,3-dihydro-1H-inden-5-yloxy)acetate 

Downstream Products

• 943116-95-8 Indanyl-5-oxyacetylchlorid 

Relevant academic research and scientific papers

NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, inflammatory disease of the joints, neuropathies, HIV-related neuropathy, nerve injury, neurodegeneration, stroke, urinary bladder hypersensitivity including urinary incontinence, cystitis, stomach duodenal ulcer, irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD), fecal urgency, gastro-esophageal reflux disease (GERD), Crohn's disease, asthma, chronic obstructive pulmonary disease, cough, neurotic/allergic/inflammatory skin disease, psoriasis, pruritus, prurigo, irritation of skin, eye or mucous membrane, hyperacusis, tinnitus, vestibular hypersensitivity, episodic vertigo, cardiac diseases such as myocardial ischemia, hair growth-related disorders such as effluvium, alopecia, rhinitis, and pancreatitis.

Design, Synthesis, and Testing of Potential Antisickling Agents. 4. Structure-Activity Relationships of Benzyloxy and Phenoxy Acids

In this paper we further establish the activity of two classes of small molecules, benzyloxy and phenoxy acids, as potent inhibitors of hemoglobin S (HbS) gelation.Structural modifications with a large number of each class confirm our earlier work that the highest activity is observed with compounds that contain dihalogenated aromatic rings with attached polar side chains.We have also found a halogenated aromatic malonic acid derivative to be quite active.Compounds reported in this paper are compared with other antigelling agents studied in our laboratory.Comments are made concerning the antigelling activity and binding sites of four derivatives and their effect on the allosteric mechanism of hemoglobin (Hb) function.