1878-69-9Relevant articles and documents
Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity
Fattorusso, Caterina,Gemma, Sandra,Butini, Stefania,Huleatt, Paul,Catalanotti, Bruno,Persico, Marco,De Angelis, Meri,Fiorini, Isabella,Nacci, Vito,Ramunno, Anna,Rodriquez, Manuela,Greco, Giovanni,Novellino, Ettore,Bergamini, Alberto,Marini, Stefano,Coletta, Massimo,Maga, Giovanni,Spadari, Silvio,Campiani, Giuseppe
, p. 7153 - 7165 (2007/10/03)
Pyrrolobenzoxazepinones (PBOs) represent a new class of human immunodeficiency virus type 1 (HIV-1) nonnucleoside reverse transcriptase (RT) inhibitors (NNRTIs) whose prototype is 5. Molecular modeling studies based on the X-ray structures of HIV-1 RT pro
Synthesis of phenylacetic acids under rhodium-catalyzed carbonylation conditions
Giroux,Nadeau,Han
, p. 7601 - 7604 (2007/10/03)
Benzyl halides are efficiently carbonylated to phenylacetic acids in the presence of a catalytic amount of the dimer of chloro(1,5-cyclooctadiene)rhodium(I) in formic acid. Under these reaction conditions, sensitive functionalities such as esters and nitriles are tolerated and the phenylacetic acids are obtained in good to high yields. (C) 2000 Elsevier Science Ltd.