1878-80-4

Usage

Uses

Used in Pharmaceutical Industry:
(3-ACETYLPHENOXY)ACETIC ACID is used as a synthetic intermediate for the production of chalcones, which possess significant antibacterial properties. These chalcones can be further developed into new antibiotics to combat bacterial infections, particularly in the context of increasing antibiotic resistance.
Used in Chemical Synthesis:
APAA serves as a key building block in the synthesis of various organic compounds, including those with potential applications in the pharmaceutical, agrochemical, and materials science industries. Its reactivity and structural diversity make it a valuable component in the development of novel molecules with specific biological activities or material properties.

InChI:InChI=1/C10H10O4/c1-7(11)8-3-2-4-9(5-8)14-6-10(12)13/h2-5H,6H2,1H3,(H,12,13)

Upstream product

• 121-71-1 3-Hydroxyacetophenone 
• 79-11-8 chloroacetic acid 
• 6951-35-5 (3-acetyl-phenoxy)-acetic acid methyl ester 
• 79-08-3 bromoacetic acid 

Downstream Products

• 113787-97-6 (m-acetylphenoxy)acetyl-L-cysteinyl-D-valine 
• 113788-00-4 (2S,5R,6R)-6-[2-(3-Acetyl-phenoxy)-acetylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 1187941-75-8 C₃₄H₃₇N₃O₉ 
• 6951-35-5 (3-acetyl-phenoxy)-acetic acid methyl ester 

Relevant academic research and scientific papers

LANTHANIDE(III) CHELATES COMPRISING BETA-DIKETONES AND CONJUGATES DERIVED THEREOF

This invention relates to luminescent lanthanide(III) chelates based on β-diketones comprising an azacycloalkane backbone and biomolecule conjugates and solid supports comprising these chelates. In contrast to lanthanide chelates based on monomeric β-diketones as well as lanthanide(III) chelates based on acyclic azaalkanes including several β-diketone subunits, the molecules of the present technology are luminescent even in the absence of additional chelators such as phosphine oxides.

2-Amido-thiazole-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof

2-Amido-4-substituted-aryl-thiazole-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme

Chalcone derivatives

The present invention provides new chalcone derivatives of the general formula: STR1 wherein R1 is a hydroxyl, carboxylic acid or sulphonic acid group or a carboxyalkoxy or sulphoalkoxy radical, R2 and R3, which may be the same or different, are hydrogen or halogen atoms, hydroxyl groups or alkoxy radicals and R4 is an alkyl, hydroxyalkyl, alkoxy, carboxyalkoxy, sulphoalkoxy or carboxyalkylcarbonyloxyalkyl radical or a carboxylic acid or sulphonic acid group, with the proviso that compounds of general formula (Ia) always contain at least one carboxylic acid or sulphonic acid group; and the non-toxic inorganic and organic salts of those compounds containing at least one carboxylic acid or sulphonic acid group, the compounds of the invention are useful for treating inflammatory and allergic conditions and for treating ulcerous conditions of the gastro-intestinal tract in humans.