18782-14-4

Downstream Products

• 84487-21-8 2-(3-Benzyl-3-hydroxy-1-methyl-4-phenyl-butyl)-4-methyl-phenol 
• 40267-33-2 3-(2-methoxy-5-methyl-phenyl)-butyric acid 
• 84487-24-1 Acetic acid 2-(3-benzyl-3-hydroxy-1-methyl-4-phenyl-butyl)-4-methyl-phenyl ester 

Relevant academic research and scientific papers

Lactone formation by rhodium-catalyzed C-C bond cleavage of cyclobutanone

As a coordinating ligand, the phenol group in appropriately substituted cyclobutanones facilitates the Rh1-catalyzed activation of the C-C bond between the carbonyl group and the α-carbon atom. This novel reaction leads, depending on the position of the phenol group on the cyclobutanone ring, to lactones of varying ring size (for example, as shown for a seven-membered-ring lactone).