187877-89-0 Usage
Cyclopentane Derivative
Yes
It is derived from cyclopentane, a five-membered ring structure.
Hydroxyl Groups
Two
The compound contains two hydroxyl (-OH) groups.
Amino Group
One
The compound has one amino (-NH2) group.
Fluorine Atom
One
The compound contains a single fluorine atom, which can contribute to its biological activity.
Chiral Molecule
Yes
The compound is chiral, meaning it has a non-superimposable mirror image.
Specific Configuration
[1S-(1α,2β,3β,4α)]-(9CI)
The compound has a specific arrangement of atoms, as indicated by the stereochemistry designation.
Pharmaceutical and Agrochemical Synthesis
Building Block
It is commonly used as a starting material or intermediate in the synthesis of pharmaceuticals and agrochemicals.
Fluorine-containing Drugs
Potential Application
The presence of a fluorine atom makes it useful in the development of fluorine-containing drugs with potential biological activity.
Unique Structure and Properties
Valuable and Versatile
The compound's structure and properties make it valuable and versatile in various industries, including the chemical, pharmaceutical, and agrochemical sectors.
Check Digit Verification of cas no
The CAS Registry Mumber 187877-89-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,8,7 and 7 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 187877-89:
(8*1)+(7*8)+(6*7)+(5*8)+(4*7)+(3*7)+(2*8)+(1*9)=220
220 % 10 = 0
So 187877-89-0 is a valid CAS Registry Number.
187877-89-0Relevant academic research and scientific papers
Synthesis of carbocyclic 2',3'-dideoxy-2'-fluoro-3'-C-hydroxymethyl nucleoside analogues as potential inhibitors of HIV and HSV
Wachtmeister, Johanna,Classon, Bjoern,Samuelsson, Bertil,Kvarnstroem, Ingemar
, p. 1861 - 1872 (2007/10/03)
The synthesis of four isomerically pure fluoro-carbocyclic adenosine and guanosine analogues is described. The 3S,4S-bis(t-butyldiphenylsilyloxymethyl)-2-fluoropentan- 1-ol derivatives 22, 23, 24 and 25 synthesised from enantiomerically pure 3S,4S-bis(t-butyldiphenylsilyloxymethyl)-cyclopentanone (18), were coupled with chloropurines using the Mitsunobu procedure to give 10, 11, 12, 14 and 16 or converted to their corresponding 1-amino derivatives, from which the fluoro-carbocyclic guanosine analogues 13, 15 and 17 were prepared. Compounds 10-17 were evaluated as potential anti-viral agents but were found to be inactive.
Synthesis of novel fluoro carbocyclic purine nucleoside analogues
Wachtmeister, Johanna,Classon, Bjoern,Kvarnstroem, Ingemar,Samuelsson, Bertil
, p. 809 - 814 (2007/10/03)
The synthesis of four isomerically pure fluoro-carbocyclic adenosine and guanosine analogues is described.
