187884-29-3Relevant academic research and scientific papers
Synthesis of 1,2,4-trioxanes and 1,2,4-trioxepanes by N-halogenosuccinimide-mediated cyclisations of unsaturated hydroperoxyacetals
Ushigoe, Yoshihiro,Kano, Yoshihiro,Nojima, Masatomo
, p. 5 - 10 (2007/10/03)
Ozonolyses of vinyl ethers 1a-c in CH2Cl2 in the presence of allylic and homoallylic alcohols 3a-c give in each case the corresponding unsaturated hydroperoxy acetals 4a-h, derived from capture of the carbonyl oxides 2a-c by the unsaturated alcohols. N-Halogenosuccinimide-mediated cyclisations of the hydroperoxides give the corresponding 1,2,4-trioxanes and/or 1,2,4-trioxepanes, depending on the structure of the hydroperoxides and the identity of the N-halogenosuccinimides.
