187931-01-7

Upstream product

• 7534-40-9 2-phenylallyl acetate 
• 100-58-3 phenylmagnesium bromide 
• 1380324-84-4 1,3-bis[tert-butyldimethylsilyloxy]-2-phenylpropan-2-ol 
• 70-11-1 α-bromoacetophenone 
• 2243-35-8 2-acetoxyacetophenone 
• 162821-38-7 5-hydroxy-5-phenyl-2,2-dimethyl-1,3-dioxane 
• 187931-00-6 3-acetoxy-1,2-dihydroxy-2-phenylpropane 

Downstream Products

• 187931-02-8 (2,2-dimethyl-4-phenyl-1,3-dioxolan-4-yl)methanol 
• 151588-91-9 C₁₆H₁₆O₄ 
• 1380324-93-5 (2,2-dimethyl-4-phenyl-1,3-dioxolan-4-yl)methyl butanoate 
• 1380325-02-9 (R)-(2,2-dimethyl-4-phenyl-1,3-dioxolan-4-yl)methyl butanoate 
• 138489-42-6 (R)-(2,2-dimethyl-4-phenyl-1,3-dioxolan-4-yl)methanol 
• 1380325-07-4 (S)-(2,2-dimethyl-4-phenyl-1,3-dioxolan-4-yl)methanol 
• 1380325-13-2 (S)-(2,2-dimethyl-4-phenyl-1,3-dioxolan-4-yl)methyl butanoate 
• 1373117-75-9 5,8-dimethyl-3-phenylquinoline 
• 1609646-83-4 N-((5-methyl-3-phenylquinolin-8-yl)methyl)-4-(trifluoromethyl)benzenesulfonamide 
• 1133797-20-2 (R)-3-(tert-butyldimethylsilyloxy)-2-phenylpropane-1,2-diol 
• 933791-92-5 C₁₂H₁₂O₃C₄H₂ 

Relevant academic research and scientific papers

Chemoenzymatic enantioselective synthesis of 2-substituted glycerol derivatives

2-Substituted glycerol derivatives 4a-g were resolved by acylation with vinyl butyrate in the presence of lipases in organic media. The reverse reaction, the enzymatic hydrolysis of the corresponding butyrates 5a-g, was also highly stereoselective and pro

Enantioselective synthesis of tertiary alcohols by the desymmetrizing benzoylation of 2-substituted glycerols

(Chemical Equation Presented) Complementary catalysts have been found for the enantioselective desymmetrization of 2-substituted glycerols by monobenzoylation with benzoyl chloride and Et3N to give chiral tertiary alcohols with 80 to 94% ee (se

A convenient synthesis of 2-phenylglycerol

1,3-Dihydroxyacetone dimer is treated with trimethylsilyl chloride and triethylamine in dichloromethane to provide monomeric ketone having both of its alcohols protected as their di-TMS ethers. The latter is added to phenylmagnesium bromide in ether at -78°C. Work-up by treatment with aqueous ammonium chloride followed by 2 N HCl provides 2-phenylglycerol in 70% yield.

Selective cation binding with cis,cis-1,3,5-trioxycyclohexyl based ligands: application to ion transport and electrochemical detection and assessment of complexation by electrospray mass spectrometry

The synthesis is reported of two sets of oxa-amide ionophores based on 2-phenylglycerol and cis,cis-cyclohexane-1,3,5-triol, with ligand coordination numbers of four, five and six.Ionophores based on the hexadentate cyclohexyl triamide 9 show excellent Na+/K+ selectivity (-logKpotNa,K=3.1), and the pentadentate analogue 10 shows good L+/Na+ selectivity (-logKpotLi,Na=2.2).Solution NMR and liquid-liquid extraction studied confirmed the formation of 1:1 complexes and IR studies pinpointed the presence of amide binding.Ligands based on 2-phenylglycerol exhibited good Ca2+ selectivity which was highest for the hexadentate triamide, 6.Detailed ESMS studies revealed similar trends in ion-binding, performed under controlled conditions.