187931-07-3Relevant academic research and scientific papers
Selective cation binding with cis,cis-1,3,5-trioxycyclohexyl based ligands: application to ion transport and electrochemical detection and assessment of complexation by electrospray mass spectrometry
Goodall, Matthew,Kelly, Patricia M.,Parker, David,Gloe, Karsten,Stephan, Holger
, p. 59 - 70 (2007/10/03)
The synthesis is reported of two sets of oxa-amide ionophores based on 2-phenylglycerol and cis,cis-cyclohexane-1,3,5-triol, with ligand coordination numbers of four, five and six.Ionophores based on the hexadentate cyclohexyl triamide 9 show excellent Na+/K+ selectivity (-logKpotNa,K=3.1), and the pentadentate analogue 10 shows good L+/Na+ selectivity (-logKpotLi,Na=2.2).Solution NMR and liquid-liquid extraction studied confirmed the formation of 1:1 complexes and IR studies pinpointed the presence of amide binding.Ligands based on 2-phenylglycerol exhibited good Ca2+ selectivity which was highest for the hexadentate triamide, 6.Detailed ESMS studies revealed similar trends in ion-binding, performed under controlled conditions.
