18794-74-6

Usage

Chemical structure

A long-chain alcohol with two octadecyloxy groups attached to a propan-2-ol backbone

Physical state

Solid at room temperature

Texture

Waxy, oily

Solubility

Insoluble in water, soluble in organic solvents like ethanol and acetone

Applications

a. Surfactant in cosmetic and personal care products
b. Lubricant and release agent in industrial applications
c. Thickening agent in some formulations

Properties

a. Surfactant and emulsifying properties
b. Wide range of applications due to its versatility

Safety

Generally considered safe for use in cosmetics and personal care products, but may cause skin irritation in some individuals

Regulatory status

Approved for use in cosmetics and personal care products by the FDA and other regulatory bodies

Synonyms

Octadecyl propoxy propanol, 1,3-Dioctadecyloxypropan-2-ol, and 1,3-Di(octadecyloxy)propan-2-ol

InChI:InChI=1/C39H80O3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-41-37-39(40)38-42-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h39-40H,3-38H2,1-2H3

Upstream product

• 112-92-5 1-octadecanol 
• 106-89-8 epichlorohydrin 
• 16245-97-9 octadecyl glycidyl ether 
• 96-23-1 1,3-Dichloro-2-propanol 
• 544-62-7 batyl alcohol 
• 31081-59-1 1-octadecyl methanesulfonate 

Downstream Products

• 854936-82-6 1-bromomethyl-4-(2-octadecyloxy-1-octadecyloxymethyl-ethoxymethyl)-benzene 
• 854936-84-8 [4-(2-octadecyloxy-1-octadecyloxymethyl-ethoxymethyl)-phenyl]-methanol 
• 854936-83-7 acetic acid 4-(2-octadecyloxy-1-octadecyloxymethyl-ethoxymethyl)-benzyl ester 
• 854936-93-9 (2R,3R,4aS,5S,7R,8R,8aS)-2,3-Dimethoxy-2,3,5-trimethyl-7-[4-(2-octadecyloxy-1-octadecyloxymethyl-ethoxymethyl)-benzyloxy]-hexahydro-pyrano[3,4-b][1,4]dioxin-8-ol 
• 854936-88-2 Phenoxy-acetic acid (2R,3R,4aS,5S,7R,8R,8aR)-2,3-dimethoxy-2,3,5-trimethyl-7-[4-(2-octadecyloxy-1-octadecyloxymethyl-ethoxymethyl)-benzyloxy]-hexahydro-pyrano[3,4-b][1,4]dioxin-8-yl ester 
• 854936-94-0 7-{2,3-dimethoxy-2,3,5-trimethyl-7-[4-(2-octadecyloxy-1-octadecyloxymethyl-ethoxymethyl)-benzyloxy]-hexahydro-pyrano[3,4-b][1,4]dioxin-8-yloxy}-2,3-dimethoxy-2,3,5-trimethyl-hexahydro-pyrano[3,4-b][1,4]dioxin-8-ol 
• 854936-89-3 phenoxy-acetic acid 7-{2,3-dimethoxy-2,3,5-trimethyl-7-[4-(2-octadecyloxy-1-octadecyloxymethyl-ethoxymethyl)-benzyloxy]-hexahydro-pyrano[3,4-b][1,4]dioxin-8-yloxy}-2,3-dimethoxy-2,3,5-trimethyl-hexahydro-pyrano[3,4-b][1,4]dioxin-8-yl ester 

Relevant academic research and scientific papers

Efficient assembly of oligomannosides using the hydrophobically assisted switching phase method

The hydrophobically assisted switching phase (HASP) method was applied in the assembly of oligomannosides. A new mannosyl donor with high reactivity was selected after a series of optimization studies, which was suitable for the synthesis of oligomannosides via the HASP method. The practicability of the HASP method towards the synthesis of branched oligosaccharides was explored and two branched penta-mannosides were assembled efficiently.

A close-packed, highly insulating organic thin monolayer on Si(111)

A long-chain dialkylated olefin, 2C18 was found to form a close-packed, highly insulating self-assembled monolayer (SAM) on Si(111) via Si-C bond formation. The IR absorption spectra of the 2C18-SAM show that the alkyl chains are densely packed with an all-trans conformation. The threshold voltage to initiate the scanned probe oxidation (SPO) of the 2C18-SAM-covered Si(111) was ca. 9V, which is much higher than the previously reported voltages for organic monolayers on Si or SiO2/Si substrates. Copyright

Hydrophobically assisted switching phase synthesis: The flexible combination of solid-phase and solution-phase reactions employed for oligosaccharide preparation

Hydrophobically assisted switching phase (HASP) synthesis is a concept that allows the choice between the advantages of solid-supported chemistry and those of solution-phase synthesis. Starting from the examination of adsorption and desorption properties of hydrophobic molecules to and from reversed-phase silica, we designed a dilipid as a quantitative and fully reversible HASP anchor, permitting final product release. The utility of this new tool in synthetic organic chemistry was demonstrated on oligosaccharide preparation. The synthesis of a pentarhamnoside was accomplished by repetitive glycosylation reactions. Glycosylations were conducted preferably in solution, whereas all protecting group manipulations were performed on solid support. Without the need for chromatographic purification of intermediates, the HASP system furnished the final product after 12 linear steps with average yields of 94% per step at a scale of 0.1 mmol, thus overcoming several of the limitations encountered in the solid-phase synthesis of complex carbohydrates. Copyright

Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents

Substituted polycarboxylic ligand molecules and corresponding metal complexes of said ligands, preferably paramagnetic metals complexes for generating responses in the field of magnetic resonance imaging (MRI). The paramagnetic complexes of the polycarboxylic ligands possess advantageous tensioactive properties and are useful as MRI contrast media in formulations for investigating the blood pool.

Synthesis of 1,3-di-O-alkyl-2-O-(β-glycosyl)glycerols bearing oligosaccharides as hydrophilic groups

A novel series of synthetic glycolipids, 1,3-di-O-alkyl-2-O-(β-glycosyl)glycerols, and their efficient synthetic route were proposed.These glyceroglycolipids were synthesized in good overall yields and stereoselectivity in five steps via trichloroacetimidate glycosylation with 1,3-di-O-alkylglycerols.This route was applied to prepare the glycolipids bearing a cello- or malto-oligosaccharide with a definite number of sugar residues from one to six.Thin-layer chromatography, elemental analysis, nuclear magnetic resonance spectroscopy and infrared absorption spectroscopy confirmed that these glycolipids were chemically pure compounds.Keywords: Glyceroglycolipids; Oligosaccharide headgroups; Synthesis

75 Se and 123m Te Compounds for fat resorption tests

The invention relates to a method of determining the fat resorption, in which a radio-active test fat and reference substance are orally administered. According to the present invention a triether or glycerol of which one or more oxygen atoms are substituted by atoms of the isotope 75 Se or 123m Te, is used as a reference substance. In a preferred embodiment use is made of 125 I- or 131 I-triolein as test fat. The proposed reference substances are novel compounds. A suitable reference substance is for example 1-butylselenyl-75 -Se-2,3-dioctadecyloxypropane.