187960-76-5Relevant academic research and scientific papers
Convergent synthesis and diversity of amino acid based dendrimers
Brouwer, Arwin J.,Mulders, Suzanne J. E.,Liskamp, Rob M. J.
, p. 1903 - 1915 (2007/10/03)
The synthesis of amino acid based dendrimers 25 (fifth generation, 32 endgroups), 30 (fourth generation, 81 endgroups), chiral dendrimer 23 (third generation, 8 endgroups) as well as core-modified dendrimers 34 and 38 by the convergent method is described. The amino acid building blocks are derived from hydroxybenzoic acid derivatives and amino alcohol derivatives, and access to a considerable molecular diversity of these novel dendrimers can be achieved, The synthesis can be carried out on a relatively large scale, and this easy access of the dendrimers may lead to many potential applications.
Sizing of amino acid based dendrimers in Langmuir monolayers
Mulders, Suzanne J. E.,Brouwer, Arwin J.,Kimkes, Peter,Sudhoelter, Ernst J. R.,Liskamp, Rob M. J.
, p. 1535 - 1538 (2007/10/03)
The size and monolayer morphology of synthesised amphiphilic amino acid based dendrimers is studied in a Langmuir trough using Brewster Angle microscopy.
Synthesis of a novel amino acid based dendrimer
Mulders, Suzanne J.E.,Brouwer, Arwin J.,Van Der Meer, Peter G.J.,Liskamp, Rob M.J.
, p. 631 - 634 (2007/10/03)
An easy accessible dendrimer monomer 3,5-bis(2-tert-butyloxycarbonyl aminoethoxy) benzoic acid methyl ester 1 was designed. The monomer was converted to both the 'surface' and 'braching' monomer in a versatile synthesis of a novel amino acid based dendrimer by the covergent method, using the well established and high-yielding BOP-peptide coupling method.
