187971-23-9Relevant academic research and scientific papers
Synthesis of alkylene linked bis-THA and alkylene linked benzyl-THA as highly potent and selective inhibitors and molecular probes of acetylcholinesterase
Pang, Yuan-Ping,Hong, Feng,Quiram, Polly,Jelacic, Tanya,Brimijoin, Stephen
, p. 171 - 176 (1997)
An efficient and economical synthesis of a series of rationally designed novel 9,9′-(alkane-1,-ω-diyldiimino)-1,2,3,4-tetrahydroacridines (ω = 7-10) and a second series of new analogues, 9-(ω-phenylalkylamino)-1,2,3,4-tetrahydroacridines (ω = 4-10), is re
THA analogs useful as cholinesterase inhibitors
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, (2008/06/13)
The present invention provides cholinesterase inhibitors of general formula (I): STR1 wherein R is H or (C 1 -C 4)alkyl, Y is a linking group and Z is an alkyl or aryl group, including heteroaryl groups, and the pharmaceutically acceptable salts thereof.
