187987-85-5

Basic information

• Product Name: 6-[(2-hydroxy-3-methoxyphenyl)(4-morpholinyl)methyl]-1,3-benzodioxol-5-ol
• CAS NO: 187987-85-5
• Molecular Weight: 359.379
• Mol File: 187987-85-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-[(2-hydroxy-3-methoxyphenyl)(4-morpholinyl)methyl]-1,3-benzodioxol-5-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[(2-hydroxy-3-methoxyphenyl)(4-morpholinyl)methyl]-1,3-benzodioxol-5-ol(187987-85-5)
• EPA Substance Registry System: 6-[(2-hydroxy-3-methoxyphenyl)(4-morpholinyl)methyl]-1,3-benzodioxol-5-ol(187987-85-5)

Safety Data

• Hazardous Substances Data: 187987-85-5(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 533-31-3 Sesamol 
• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 

Downstream Products

• 117211-16-2 (6S,7S,8R)-8-(2-Hydroxy-3-methoxy-phenyl)-7-methyl-7,8-dihydro-6H-[1,3]dioxolo[4,5-g]chromen-6-ol 
• 117211-16-2 (6R,7S,8R)-8-(2-Hydroxy-3-methoxy-phenyl)-7-methyl-7,8-dihydro-6H-[1,3]dioxolo[4,5-g]chromen-6-ol 

Relevant articles and documents

New Anti-tumor Agents. 2. Benzopyranylamine Compounds

Pyrrolidine, morpholine and piperidine derived Mannich bases of types 1-3 react with acetone, propionaldehyde and butyraldehyde to form 2-methyl and 3-methylbenzopyrans of types 4-8. Hydrolysis of these benzopyrans yields alcoholic benzopyrans which readily condense with a variety of amine, aniline and hydrazine derivatives to form diverse isomeric benzopyrans of types of 9 and 10. The benzopyrans 4-9 which contain a 3,4,5-trimethoxyphenyl ring are active anti-tumor agents, particularly against human breast, CNS and colon cancer cell lines, total growth inhibition of these tumors often occurring in vitro at concentrations as low as 10-5-10-6 moles/l. Because of their in vitro activities and unusual structures a number of these benzopyrans have been selected for in vivo Xenograft testing against breast and other susceptible human cancers.