187992-17-2Relevant articles and documents
Discovery of new diphenyloxazole derivatives containing a pyrrolidine ring: Orally active prostacyclin mimetics. Part 2
Hattori, Kouji,Okitsu, Osamu,Tabuchi, Seiichiro,Taniguchi, Kiyoshi,Nishio, Mie,Koyama, Satoshi,Seki, Jiro,Sakane, Kazuo
, p. 3279 - 3283 (2007/10/03)
Synthetic and biological evaluation of novel diphenyloxazole derivatives containing a pyrrolidine ring, as a prostacyclin mimetic without the PG skeleton, are described. Asymmetric reduction of a ketone using a chiral Ru complex and reductive amination by