188011-04-3

Basic information

• Product Name: 2,2,3,3,4,4,4-heptafluoro-N-p-tolyl-butyramide
• CAS NO: 188011-04-3
• Molecular Weight: 303.179
• Mol File: 188011-04-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2,3,3,4,4,4-heptafluoro-N-p-tolyl-butyramide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,3,3,4,4,4-heptafluoro-N-p-tolyl-butyramide(188011-04-3)
• EPA Substance Registry System: 2,2,3,3,4,4,4-heptafluoro-N-p-tolyl-butyramide(188011-04-3)

Safety Data

• Hazardous Substances Data: 188011-04-3(Hazardous Substances Data)

Upstream product

• 375-16-6 heptafluorobutyryl chloride 
• 106-49-0 p-toluidine 
• 43183-36-4 1-(trimethylsilyl)-1H-benzotriazole 

Downstream Products

• 887335-90-2 2,2,3,3,4,4,4-heptafluoro-N-p-tolyl-butyrimidoyl chloride 

Relevant articles and documents

N-acylbenzotriazoles: Neutral acylating reagents for the preparation of primary, secondary, and tertiary amides

Readily available N-acylbenzotriazoles 2a-q efficiently acylate aqueous ammonia and primary and secondary amines to give primary, secondary, and tertiary amides in good to excellent yields. The wide applicability of the procedure is illustrated by the preparation of (i) α-hydroxyamides from α-hydroxy acids and of (ii) perfluoroalkylated amides.