188015-18-1Relevant academic research and scientific papers
Intramolecular Diels-Alder Reaction of 2-Cyano-1-aza-1,3-butadienes
Sisti, Nicholas J.,Zeller, Emmanuel,Grierson, David S.,Fowler, Frank W.
, p. 2093 - 2097 (1997)
It has been demonstrated that a 2-cyano substituent is sufficient to activate 1-aza-1,3-butadienes with respect to the intramolecular Diels-Alder reaction. This reaction is successful for the preparation of the indolizidine and quinolizidine ring systems. The stereochemistry of the isomeric products was assigned by a careful analysis of their NMR spectral data.
