188019-80-9Relevant academic research and scientific papers
Synthesis of 4-substituted- and 1,4-disubstituted-4-hydroxypyrrolidin-2- ones
Kinsinger, Christopher R.,Tatko, Chad D.,Whelan, Christopher M.,Wilkinson, Timothy J.
, p. 1845 - 1852 (2008/02/02)
This report describes the synthesis of 4-substituted- and 1,4-disubstituted-4-hydroxypyrrolidin-2-ones by cyclization of intermediate γ-aminoesters prepared from alkylbenzylamines, α-bromoketones, and lithio ethyl acetate. Copyright Taylor & Francis Group, LLC.
