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6-AZAURACIL, a derivative of uracil with the molecular formula C3H4N2O2, is a chemical compound that features an additional nitrogen atom in its five-membered ring structure. Known for its potent antimetabolite properties, 6-AZAURACIL inhibits the enzyme orotidine monophosphate decarboxylase, thereby disrupting the synthesis of pyrimidine nucleotides. This disruption has significant implications for its potential use in cancer therapy, as it can interfere with the DNA and RNA synthesis of rapidly dividing cells. Furthermore, 6-AZAURACIL has demonstrated antiviral activity against certain RNA viruses, and ongoing research is exploring its therapeutic potential in treating a range of diseases.

18802-37-4

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18802-37-4 Usage

Uses

Used in Cancer Therapy:
6-AZAURACIL is used as an antimetabolite agent for its ability to inhibit the synthesis of pyrimidine nucleotides, which is crucial for the DNA and RNA synthesis in rapidly dividing cancer cells. This action can lead to the disruption of these processes, potentially contributing to the suppression of tumor growth.
Used in Antiviral Applications:
6-AZAURACIL is used as an antiviral agent for its demonstrated activity against certain RNA viruses. By interfering with the replication and transcription processes of these viruses, 6-AZAURACIL may help in controlling viral infections and reducing their impact on the host.
Used in Pharmaceutical Research:
6-AZAURACIL is used as a subject of research for its potential therapeutic applications in the treatment of various diseases. Ongoing studies aim to understand its mechanisms of action and to identify new ways in which it can be utilized to combat different health conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 18802-37-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,8,0 and 2 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18802-37:
(7*1)+(6*8)+(5*8)+(4*0)+(3*2)+(2*3)+(1*7)=114
114 % 10 = 4
So 18802-37-4 is a valid CAS Registry Number.
InChI:InChI=1/C3H5N3O2/c7-2-1-4-6-3(8)5-2/h4H,1H2,(H2,5,6,7,8)

18802-37-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-AZAURACIL

1.2 Other means of identification

Product number -
Other names 5-Amino-1,2,4-triazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18802-37-4 SDS

18802-37-4Downstream Products

18802-37-4Relevant academic research and scientific papers

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