188051-24-3

Upstream product

• 128454-47-7 monoallyl succinic acid chloride 
• 141-86-6 2.6-diaminopyridine 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 220891-73-6 (S)-2-Amino-N-(6-amino-pyridin-2-yl)-3-phenyl-propionamide 
• 188051-21-0 (4S)-4-tert-Butoxycarbonyl-4-benzyl-3-oxo-11,4-diamino-12,2-diaza-1(1,3)-benzatetraphane 

Downstream Products

• 188051-31-2 N-{(S)-1-[6-(2-{4'-[4-(tert-Butoxycarbonylamino-methyl)-phenoxymethyl]-biphenyl-4-yl}-acetylamino)-pyridin-2-ylcarbamoyl]-2-phenyl-ethyl}-succinamic acid allyl ester 

Relevant academic research and scientific papers

Synthesis and binding properties of a macrocyclic peptide receptor

Macrocyclic receptor 1 has been synthesised, as a racemate and as a single enantiomer, utilising a Stille coupling for the formation of the biphenyl portion and a macrolactamisation as the final step. The binding properties for the racemic and the homochi

Modified synthesis and binding properties of a peptide receptor

Macrocyclic receptor 9, has been prepared in homochiral form. The receptor shows selectivity for certain dipeptides, and most notably a strong preference for N-Cbz-β-alanyl amino acids over N-Cbz-β-alanyl lactic acids.