18818-30-9

Usage

Uses

Used in Organic Synthesis:
1-(4-Methyl-1H-pyrrol-3-yl)ethanone is used as a key intermediate in the synthesis of organic molecules for various applications due to its reactivity and ability to form complex chemical structures.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-(4-Methyl-1H-pyrrol-3-yl)ethanone is used as a building block for the development of new drugs, leveraging its chemical properties to create novel therapeutic agents.
Used in Fragrance and Flavor Production:
1-(4-Methyl-1H-pyrrol-3-yl)ethanone is used as a component in the creation of fragrances and flavors, enhancing the characteristic smell and taste profiles of certain compounds.
Safety Considerations:
It is crucial to handle 1-(4-Methyl-1H-pyrrol-3-yl)ethanone with care and adhere to proper safety protocols during its use, given the potential hazards related to its reactivity and toxic properties.

Upstream product

• 79720-71-1 3-acetyl-4-methyl-pyrrole-2-carboxylic acid 
• 625-33-2 3-penten-2-one 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 33423-48-2 4-acetyl-5-formyl-3-methyl-1H-pyrrole-2-carboxylic acid ethyl ester 
• 86925-92-0 astepyrone 
• 858272-30-7 3-acetyl-4-methyl-pyrrole-2,5-dicarboxylic acid-5-ethyl ester 
• 51741-06-1 3-acetyl-2-dichloromethyl-5-ethoxycarbonyl-4-methylpyrrole 

Downstream Products

• 112381-10-9 4-acetyl-3-methyl-1H-pyrrole-2-carbonitrile 
• 202286-27-9 3-acetyl-4-methyl-5-bromo-1H-pyrrole 

Relevant academic research and scientific papers

Synthesis of the Ring C Pyrrole of Native Chlorophylls and Bacteriochlorophylls

As part of a program to develop practical syntheses of members of the family of (bacterio)chlorophylls, two routes to 2-iodo-3-methyl-4-(3-methoxy-1,3-dioxopropyl)pyrrole, a precursor of the universal ring C, have been developed. The β-ketoester of ring C

Unusually Facile Thermal Homodienyl-[1,5]-Hydrogen Shift Reactions in Photochemically Generated Vinyl Aziridines

A range of photochemically generated tri- and tetracyclic vinyl aziridines have been found to undergo a general and surprisingly low temperature ring opening through a [1,5]-hydrogen shift reaction. The rate of the process was found to be highly dependent on the structure and substitution around the azirdine ring and the alkene terminus, with some substrates being observed to undergo ring opening at temperatures as low as 25 °C. The rigid nature of these polycyclic systems precludes a conformational explanation of these rate differences, and an Eyring study confirmed a negligible entropic barrier to the reaction. However, the Eyring plots for two different aziridines systems showed a significant difference in their enthalpies of activation. It is therefore believed that the levels of aziridine ring strain, as well as electronic effects, are the dominant factors in this sequence.

Metabolic products of Aspergillus terreus. VIII. Astepyrone: A novel metabolite of the strain IFO 4100

A novel metabolite named astepyrone and two other new metabolites were isolated from Aspergillus terreus IFO 4100, and their chemical structures were determined. The biosynthesis of astepyrone was also studied and this metabolite was proved to be formed t