188199-17-9

Upstream product

• 188199-15-7 (2R,3S,6S)-6-(2-Methyl-cyclohex-2-enyl)-2-((3aR,3bS,7R,7aR,8aR)-2,2,5,5-tetramethyl-tetrahydro-[1,3]dioxolo[4,5]furo[3,2-d][1,3]dioxin-7-ylmethoxymethyl)-3,6-dihydro-2H-pyran-3-ol 
• 188199-02-2 Trifluoro-methanesulfonic acid (2R,3S,6S)-3-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-6-(2-methyl-cyclohex-2-enyl)-3,6-dihydro-2H-pyran-2-ylmethyl ester 
• 188198-99-4 (2R,3S,6S)-6-(2-Methyl-cyclohex-2-enyl)-2-trityloxymethyl-3,6-dihydro-2H-pyran-3-ol 
• 188199-13-5 Dimethyl-[(2R,3S,6S)-6-(2-methyl-cyclohex-2-enyl)-2-((3aR,3bS,7R,7aR,8aR)-2,2,5,5-tetramethyl-tetrahydro-[1,3]dioxolo[4,5]furo[3,2-d][1,3]dioxin-7-ylmethoxymethyl)-3,6-dihydro-2H-pyran-3-yloxy]-(1,1,2-trimethyl-propyl)-silane 
• 188199-00-0 Dimethyl-[(2R,3S,6S)-6-(2-methyl-cyclohex-2-enyl)-2-trityloxymethyl-3,6-dihydro-2H-pyran-3-yloxy]-(1,1,2-trimethyl-propyl)-silane 
• 188199-01-1 [(2R,3S,6S)-3-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-6-(2-methyl-cyclohex-2-enyl)-3,6-dihydro-2H-pyran-2-yl]-methanol 

Relevant academic research and scientific papers

Hexose keto-C-glycoside conjugates: Design, synthesis, cytotoxicity, and evaluation of their affinity for the glucose transporter glut-1

The design, synthesis, cytotoxicity, and biological evaluation of carbohydrate/C-glycoside conjugates are described. The design concept is predicted on the idea that physiological barriers like the blood brain barrier could be crossed selectively by using glucose or glucose derivative/drug conjugates. The study demonstrates that, (1) carbohydrates and C-glycosides can be bonded at nonanomeric positions by the reaction of carbohydrate triflates with C-glycoside alkoxydes in the presence of DMPU; (2) there is a structure-activity relationship between the cytotoxicity of the conjugate and the nature of the carbohydrate residue; and (3) peracetylated hexose keto-C-glycoside conjugates are the most cytotoxic keto-glycosides.