188290-13-3

Upstream product

• 188290-11-1 (5S)-5-(4-methoxybenzyloxymethyl)tetrahydro-2-furanone 
• 64-04-0 phenethylamine 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 188290-12-2 (S)-4-Hydroxy-5-(4-methoxy-benzyloxy)-pentanoic acid phenethyl-amide 

Downstream Products

• 188290-16-6 Acetic acid (S)-3-(tert-butyl-dimethyl-silanyloxy)-6-oxo-1-phenethyl-piperidin-2-yl ester 
• 188290-14-4 (S)-4-(tert-Butyl-dimethyl-silanyloxy)-5-hydroxy-pentanoic acid phenethyl-amide 

Relevant academic research and scientific papers

Asymmetric synthesis of functionalized benzo[a]quinolizine derivatives via a diastereoselective N-acyliminium ion cyclization

A chiral synthesis of functionalized benzo[a]quinolizine derivative (5) has been accomplished starting from a chiral lactone 7. The key feature is the efficient control of the stereochemistry of ring juncture of the functionalized benzo[a]quinolizine derivative 5 by the N-acyliminium ion cyclization of chiral lactam 11b.