188296-71-1

Basic information

• Product Name: 6-Oxo-6-piperidin-1-yl-hexanoic acid phenylamide
• CAS NO: 188296-71-1
• Molecular Weight: 288.39
• Mol File: 188296-71-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-Oxo-6-piperidin-1-yl-hexanoic acid phenylamide(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Oxo-6-piperidin-1-yl-hexanoic acid phenylamide(188296-71-1)
• EPA Substance Registry System: 6-Oxo-6-piperidin-1-yl-hexanoic acid phenylamide(188296-71-1)

Safety Data

• Hazardous Substances Data: 188296-71-1(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 34413-03-1 6-Anilino-6-oxohexanoic acid 
• 62-53-3 aniline 
• 56384-34-0 N-phenyl-adipamic acid ethyl ester 
• 1071-71-2 ethyl 6-chloro-6-oxohexanoate 

Downstream Products

• 188296-96-0 2-(N-Phenylimino)cyclopentanecarboxylic acid 

Relevant articles and documents

Intramolecular Vilsmeier processes: a new route to cyclopenta- and cyclohexa-fused quinolines by cyclisation of adipic and pimelic bis-amides

Symmetrical and unsymmetrical bis-amides derived from adipic and pimelic acid and secondary amines react in POCl3 solution to give the title compounds by way of a Vilsmeier reagent-α-chloro enamine interaction.Adipanilide and pimelanilide only cyclise with added PCl5.However the bis-N-substituted derivatives (N-methyl or N-phenyl) of adipanilide and pimelanilide give quinolinium salts in good yield.Unsymmetrical amides with an N-substituted anilide at one end and an aliphatic unit at the other only proceed as far as the intermediate stage, giving 1,2-disubstituted cyclo-pentanes or -hexanes.Analogous amides derived from suberic and sebacic acid do not give quinolinium salts but instead give complex mixtures.