18830-58-5Relevant academic research and scientific papers
Inhibition of monoamine oxidase B by selected benzimidazole and caffeine analogues
van den Berg, Deidre,Zoellner, Kevin R.,Ogunrombi, Modupe O.,Malan, Sarel F.,Terre'Blanche, Gisella,Castagnoli Jr., Neal,Bergh, Jacobus J.,Petzer, Jacobus P.
, p. 3692 - 3702 (2008/02/07)
We have recently reported that a series of (E)-8-styrylcaffeines and (E)-2-styrylbenzimidazoles are moderate to very potent competitive inhibitors of monoamine oxidase B (MAO-B). The most potent member of the series was found to be (E)-8-(3-chlorostyryl)c
Synthesis and A1-adenosine receptors affinities of purino[7,8- c]quinazoline-8,10(9H,11H)-diones as rigid analogues of 8-arylxanthines
Ceccarelli,D'Alessandro,Magnante,Scuri,Zanarella
, p. 1301 - 1312 (2007/10/02)
Title compounds were prepared by a cyclocondensation reaction between 8- (2-aminophenyl)xanthines and trialkyl orthoesters. Some of them showed activities as A1-adenosine receptor antagonists with binding values in the micromolar range. Results
