188302-67-2Relevant academic research and scientific papers
Synthesis of azetidines by electrophilic selenium-induced cyclization of homoallylic benzylamines
Berthe, Benedicte,Outurquin, Francis,Paulmierz.ast, Claude
, p. 1393 - 1396 (2007/10/03)
Homoallyl benzylamines prepared by allylation of the corresponding N-benzylimines, have been subjected to a selenium-induced cyclization under various conditions. At room temperature. the 4-exo and the 5-endo modes are competitive. In acetonitrile, the azetidine has been isolated as the major cyclization product, especially for homoallylamines derived from ketimines. With an excess or selenium reagent, 3-halopyrrolidines have been obtained.
Synthesis of Functionalized Pyrrolidines from N-(Benzylidene)- and N-(Alkylidene)-homoallylamines
Smaele Dirk De,Kimpe, Norbert De
, p. 2029 - 2030 (2007/10/02)
N-(Benzylidene)- and N-(alkylidene)-homoallylamines are cyclised by electrophiles, e.g. bromine or phenylselenenyl bromide, and by subsequent reduction to the corresponding 3-functionalised pyrrolidines; the stereochemistry was investigated, and reductive
