188359-31-1

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 423771-87-3 C₆₇H₁₂₀O₁₃SSi₂ 
• 423771-82-8 C₇₆H₁₄₀O₁₄SSi₃ 
• 423771-79-3 C₇₅H₁₄₂O₁₄SSi₃ 
• 423771-80-6 5-(tert-butyl-dimethyl-silanyloxy)-25-(3,4-dimethoxy-benzyloxymethoxy)-9,15-dimethoxy-26-(5-methoxy-3-methyl-tetrahydro-furan-2-yl)-4,6,13,20,22-pentamethyl-3-methylsulfanylmethoxy-19,21-bis-triethylsilanyloxy-heptacosa-10,16-dien-1-ol 
• 423771-81-7 5-(tert-butyl-dimethyl-silanyloxy)-25-(3,4-dimethoxy-benzyloxymethoxy)-9,15-dimethoxy-26-(5-methoxy-3-methyl-tetrahydro-furan-2-yl)-4,6,13,20,22-pentamethyl-3-methylsulfanylmethoxy-19,21-bis-triethylsilanyloxy-heptacosa-10,16-dienal 
• 423771-86-2 C₆₈H₁₂₀O₁₃SSi₂ 
• 423771-83-9 9-(tert-butyl-dimethyl-silanyloxy)-29-(3,4-dimethoxy-benzyloxymethoxy)-23,25-dihydroxy-13,19-dimethoxy-30-(5-methoxy-3-methyl-tetrahydro-furan-2-yl)-8,10,17,24,26-pentamethyl-7-methylsulfanylmethoxy-hentriaconta-2,4,14,20-tetraenoic acid ethyl ester 
• 423771-84-0 9-(tert-butyl-dimethyl-silanyloxy)-29-(3,4-dimethoxy-benzyloxymethoxy)-23,25-dihydroxy-13,19-dimethoxy-30-(5-methoxy-3-methyl-tetrahydro-furan-2-yl)-8,10,17,24,26-pentamethyl-7-methylsulfanylmethoxy-hentriaconta-2,4,14,20-tetraenoic acid 
• 423772-64-9 10-(tert-butyl-dimethyl-silanyloxy)-26-[4-(3,4-dimethoxy-benzyloxymethoxy)-5-(5-methoxy-3-methyl-tetrahydro-furan-2-yl)-1-methyl-hexyl]-24-hydroxy-14,20-dimethoxy-9,11,18,25-tetramethyl-8-methylsulfanylmethoxy-oxacyclohexacosa-3,5,15,21-tetraen-2-one 
• 423771-85-1 10-(tert-butyl-dimethyl-silanyloxy)-24-[6-(3,4-dimethoxy-benzyloxymethoxy)-2-hydroxy-7-(5-methoxy-3-methyl-tetrahydro-furan-2-yl)-1,3-dimethyl-octyl]-14,20-dimethoxy-9,11,18-trimethyl-8-methylsulfanylmethoxy-oxacyclotetracosa-3,5,15,21-tetraen-2-one 
• 10236-14-3 4-(diethoxyphosphoryl)-but-2-enoic acid ethyl ester 
• 188359-30-0 (2R,3R)-2-[(1S,2R,5S,6S,7R,8S)-10-Benzenesulfonyl-2-(3,4-dimethoxy-benzyloxymethoxy)-1,5,7-trimethyl-6,8-bis-triethylsilanyloxy-decyl]-5-methoxy-3-methyl-tetrahydro-furan 
• 188359-29-7 2,2-Dimethyl-propionic acid (E)-(3R,4R,5R,6R,9S,13R,15R)-5-(tert-butyl-dimethyl-silanyloxy)-9,15-dimethoxy-4,6,13-trimethyl-3-methylsulfanylmethoxy-16-oxo-hexadec-10-enyl ester 

Downstream Products

• 423771-99-7 C₇₇H₁₄₄O₁₃Si₄ 
• 423771-94-2 C₇₃H₁₃₂O₁₄Si₃ 
• 423771-88-4 C₇₅H₁₃₆O₁₄SSi₃ 

Relevant academic research and scientific papers

Cytotoxicity and actin-depolymerizing activity of aplyronine A, a potent antitumor macrolide of marine origin, and its analogs

Artificial analogs of aplyronine A (1), a potent antitumor macrolide, were synthesized and structure-activity (cytotoxicity and actin-depolymerizing activity) relationships were investigated; the side-chain in 1 was found to play a key role in both biological activities.

Cytotoxicity and actin depolymerizing activity of aplyronine A, a potent antitumor macrolide of marine origin, and the natural and artificial analogs

The artificial analogs of aplyronine A (1), a potent cytotoxic and antitumor macrolide, were synthesized and the structure-activity (cytotoxicity and actin depolymerizing activity) studies were performed; the side chain portion in 1 was found to play a key role in both biological activities.