188407-92-3Relevant academic research and scientific papers
Stereoselective synthesis of (R)- and (S)-2-methyl-3-oxo-3,4-dihydro- 2H-1,4-benzoxazine-2-carboxylic acids, -carboxylates and -carboxamides
Breznik, Matej,Hrast, Valentina,Mrcina, Alenka,Kikelj, Danijel
, p. 153 - 167 (2007/10/03)
(R)-Monomethyl 2-methyl-2-(2-nitrophenoxy)malonates obtained by PLE catalyzed hydrolysis of the corresponding dimethyl malonates undergo solvent- dependent enantioselective cyclization to afford (R)-methyl 2-methyl-3-oxo- 3,4-dihydro-2H-1,4-benzoxazine-2-
Pig liver esterase catalyzed hydrolysis of dimethyl and diethyl 2-methyl-2-(o-nitrophenoxy)malonates
Breznik, Matej,Kikelj, Danijel
, p. 425 - 434 (2007/10/03)
Pig liver esterase (PLE) catalyzed hydrolysis of dimethyl and diethyl 2-methyl-2-(o-nitrophenoxy)malonates affords (R)-monoethyl/monomethyl 2-methyl-2-(o-nitrophenoxy)malonates in moderate to good enantiomeric excesses (69-81%). These data indicate that t
