188437-96-9 Usage
Uses
Used in Pharmaceutical Industry:
2-(4-bromophenyl)-Furo[3,2-c]pyridine is used as a building block for the synthesis of novel drug candidates due to its unique molecular structure and potential biological activities. Its presence in drug development may contribute to the creation of new treatments for various diseases, particularly those that are resistant to current therapies.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 2-(4-bromophenyl)-Furo[3,2-c]pyridine serves as a research chemical, aiding scientists in understanding its antimicrobial, antifungal, and anti-cancer properties. This knowledge can be instrumental in designing more effective and targeted therapies.
Used in Antimicrobial Applications:
2-(4-bromophenyl)-Furo[3,2-c]pyridine is used as an antimicrobial agent for its potential to combat resistant bacterial strains. Its unique structure may allow it to target specific pathways in microbes, offering a new approach to treating infections.
Used in Antifungal Applications:
As an antifungal agent, 2-(4-bromophenyl)-Furo[3,2-c]pyridine may be utilized to develop treatments for fungal infections, providing an alternative to existing antifungal drugs and addressing the issue of drug resistance in fungi.
Used in Anti-cancer Applications:
2-(4-bromophenyl)-Furo[3,2-c]pyridine is used as a potential anti-cancer agent, with its structure suggesting it may interact with cellular processes in ways that inhibit tumor growth or enhance the effectiveness of existing cancer therapies. Further research is necessary to determine its specific mechanisms of action and therapeutic potential in oncology.
Check Digit Verification of cas no
The CAS Registry Mumber 188437-96-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,4,3 and 7 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 188437-96:
(8*1)+(7*8)+(6*8)+(5*4)+(4*3)+(3*7)+(2*9)+(1*6)=189
189 % 10 = 9
So 188437-96-9 is a valid CAS Registry Number.
188437-96-9Relevant academic research and scientific papers
Synthesis and reactivity of aryl(alkynyl)iodonium salts
Dixon, Luke I.,Carroll, Michael A.,Gregson, Thomas J.,Ellames, George J.,Harrington, Ross W.,Clegg, William
, p. 2334 - 2345 (2013/05/21)
The first practical, yet simple, preparation of aryl(alkynyl)iodonium trifluoroacetate salts is described. The generic nature of this synthetic method has allowed the production of a range of aryl(alkynyl)iodonium trifluoroacetate salts with independent variation of both the alkynyl and aryliodo groups in yields of 30-85 %. Application of these new reagents to the synthesis of a series of 2-arylfuro[3,2-c]pyridines (40-64 %) highlights the potential of this class of materials as precursors to bioactive heterocyclic structures. These experiments have also demonstrated that, in this case, the effect of the aryliodo group on the reaction is negligible.
Synthesis of 2-arylfuro[3,2-c]pyridines and their derivatives
Krutosikova, Alzbeta,Sleziak, Robert
, p. 1627 - 1636 (2007/10/03)
A series of 2-arylfuro[3,2-c]pyridines was synthesized. 3-(5-Aryl-2-furyl)propenoic acids 1a-1h were converted to the acid azides 2a-2h, which in turn were cyclized to give 2-arylfuro[3,2-c]pyridine-4(5H)-ones 4a-4h by heating in Dowtherm. The pyridones 4a-4f were aromatized with phosphorus oxychloride to the 2-aryl-4-chlorofuro[3,2-c]pyridines 5a-5f, which were reduced with zinc and acetic acid to the title compounds 6a-6f. Reacted with phosphorus(V) sulfide, the pyridones 4a-4f yielded the corresponding thiones 7a-7f.
